DSIP

7.7

Weight Loss

7.0/10

Improved Sleep

8.5/10

Regulates Blood Pressure

7.5/10

DSIP

Fertility
Hormone Production
Mental Health
Sleep

Description

Summary

DSIP, also known as delta sleep-inducing peptide (DSIP), is a sleep-promoting factor which was isolated from rabbit cerebral venous blood in 1977 [1]. In addition to having the ability to promote or induce sleep in animals, DSIP also elicits effects such as thermoregulation, modification in heart rate, blood pressure, and pain [2]. Moreover, DSIP is considered an endogenous neuropeptide which can cross the blood-brain barrier [3].

Structure

Figure 1. Delta sleep-inducing peptide (DSIP). DSIP is known as a sleep-promoting substance and not a sedative [4]. Source: [5]

How it works

Interestingly, DSIP injection boosts the survival rate of animals under emotional stress and balances various physiological parameters [6]. The way DSIP works is through the activation, or switching on, of the serotonergic system of the brain. Then, DSIP increases the activity of monoamine oxidase A (MAO-A) – using serotonin as a substrate – in the mitochondria (the powerhouse of the cell) [7]. DSIP can cross the blood brain barrier and also can be absorbed by the human gut with being broken down by gut enzymes [4].

Additional information

Weight 0.001 kg

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DSIP

DSIP

Fertility
Hormone Production
Mental Health
Sleep