Gonadorelin is a 10-amino acid synthetic peptide with a structure that is similar to the natural Gonadotrophin-releasing hormone in various mammalian species . Moreover, gonadorelin is the hypothalamic-releasing factor which is responsible for releasing gonadotrophins from the anterior pituitary . Gonadorelin stimulates the production of and release of pituitary gonadotrophins, luteinizing hormone and follicle stimulating hormone .
Figure 1. Gonadorelin consists of 10 amino acids, and has the formula of C55H75N17O13. Gonadorelin has a half-life of around between 10-40 minutes. Source: .
How it works
Gonadorelin releasing hormone release/secretion impacts, or switches on, the acute release of luteinizing hormone (LH) and follicle stimulating hormone (FSH) . The way gonadorelin works is that it stimulates release from the luteinizing hormone and follicle stimulating hormone in the anterior pituitary gland . According to the European Agency for the Evaluation of Medicinal Products, the committee for veterinary medicinal products recommends that gonadorelin is used for the treatment of reproductive disorders in cows, and for treating the production of ovulation in rabbits .