GHRP-2

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GHRP-2

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Description

Summery

Growth-hormone-releasing peptide (GHRP)-2 is a well-known and documented peptide, discovered in 1993, that comes from the family of GHRP [1]. Growth hormone releasing compounds are a group of compounds, usually peptides consisting of four to seven amino acids, which induce elevated growth hormone levels in circulation [2]. These peptides harbour the ability to stimulate and release growth hormone in the body’s circulation [3]. In Japan, GHRP-2 is an approved pharmaceutical agent used as an intravenous injection to breast juvenile growth failure [2], and also for use the diagnosis of GH deficiency [4; 5]. GHRP-2 is also known as Pralmorelin [6].

Structure

GHRPs are known to bind to two receptors or ‘sites’, one is the GHS-R1a and the other is CD36 [7]. Furthermore, GHRPs can decrease relative oxygen species (ROS), along with enhancing antioxidant defences and reducing inflammation [7]. GHRP-2 (Figure 1) has the amino acid  sequence: (D-Ala)-(D-β -Nal)-Ala-Trp-(D-Phe)-Lys-NH2 [1].

Figure 1. GHRP-2 is derived from, and belongs to, a class of growth hormone releasing peptides which play roles in stimulating the release of growth hormone (GH) along with increasing body weight across a number of animal species. In addition GHRP-2 has been previously shown to enhance the growth rate in children [8]. Source: https://en.wikipedia.org/wiki/Pralmorelin

How it works

GHRP-2, as previously stated, is a synthetic peptide which acts as an agonist to the GHS receptor [9]. Moreover, GHRP-2 stimulates the release of growth hormone by eliciting effects at the hypothalamic and pituitary sites [10].

Additional information

Weight 0.001 kg

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GHRP-2

GHRP-2

Build Muscle
Increase Appetite
Strength