Goal Page

Fat Loss & Recomp

Updated April 3, 2026

Goal Definition

Peptides researched for fat-mass reduction, body recomposition, and lipolytic signalling. This goal page collects compounds investigated for their effects on adipose metabolism, including GLP-1 receptor agonists (semaglutide, tirzepatide, retatrutide), GH-fragment lipolytic peptides (Fragment 176-191, AOD-9604, tesamorelin), and dual/triple agonists targeting energy expenditure and substrate partitioning.

Peptides Mapped to This Goal

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Fat Loss & Recomp

Peptide Ranking by Research Score

Fat Loss Support

🥇 Retatrutide

8.5/10

🥈 Tirzepatide

8.0/10

🥉 Semaglutide

7.5/10

Tesamorelin

7.5/10

CJC-1295

7.0/10

Liraglutide

7.0/10

Ipamorelin

6.5/10

Adipotide

6.0/10

Amycretin

6.0/10

AOD-9604

6.0/10

Cagrilintide

6.0/10

Danuglipron

6.0/10

Dulaglutide

6.0/10

Exenatide

6.0/10

GHRP-2

6.0/10

HGH Fragment 176-191

6.0/10

IGF-1 DES

6.0/10

IGF-1 LR3

6.0/10

Mazdutide

6.0/10

MOTS-c

6.0/10

Orforglipron

6.0/10

Pemvidutide

6.0/10

Sermorelin

6.0/10

Survodutide

6.0/10

Scores reflect available research evidence. Research use only.

Medical Disclaimer

The content on PeptideGuide is for informational and educational purposes only and is not medical advice. It is not intended to diagnose, treat, cure, or prevent any condition. Always consult a qualified healthcare professional before making health decisions.