ACE 083

8

Muscle Growth

8.5/10

Increased Strength

9.0/10

Well Being

6.5/10

ACE 083

Build Muscle
Strength

Description

Summary

ACE-083 is known as a follistatin-based therapeutic which binds to myostatin, along with other regulators of muscle [1]. In addition, ACE-083 belongs to the TGF-β superfamily and is administered as a local injection to increase muscle mass and strength [2]. ACE-083 is currently in clinical trials stages awaiting more data to confirm its therapeutic potential in certain human diseases. Currently, ACE-083 is being assessed and evaluated for its therapeutic role in skeletal muscle growth.

Structure

Figure 1. ACE-83 works by binding ligands such as myostatin (GDF8) and other factors and molecules which work by inhibiting skeletal muscle growth [3].

How it works

ACE-083 is known as a follistatin-based therapeutic [1]. Follistatin has been described as a protein which inhibits follicle-stimulating hormone release [4]. Specifically, ACE-083 works by binding to activin and myostatin and inhibiting their signalling [5]. Activin and myostatin belong to a protein superfamily which are responsible for playing roles in regulating skeletal muscle mass [6].

Additional information

Weight 0.001 kg

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ACE 083

ACE 083

Build Muscle
Strength